Coronary artery with atherosclerosis (fibrous plaque). The atheromatous fibrous plaque is localized in the intima of the artery, beneath the endothelium, producing the thickening of the wall and, secondary, the narrowing of the lumen and the atrophy of the muscular layer by compression. The fibrous plaque contains collagen fibres (eosinophilic), precipitates of calcium (hematoxylinophilic) and rare lipid-laden cells
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