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Thyroid Examination
- Hand hygiene
- Introduce self, gain consent and cooperation.
- Ensures patient seated in good light, with access to examine from behind and
- appropriate exposure of the neck.
From end of bed
- Is patient dressed appropriately for room temp?
- Composure – hyperactivity, fidgety & restless (hyperthyroid);
- immobile & uninterested (hypothyroid)
- Observes patient from any obvious lumps/swellings.
- Asks patient to swallow to check upward movement of thyroid gland and to ascertain whether any visible lumps/swellings ascend with the thyroid.
Hands
- Increased sweating (due to hyperthyroidism)
- Palmar erythema (due to hyperthyroidism)
- Thyroid acropachy (Grave’s disease)
- Onycholysis (Plummer’s nails) – hyperthyroid
- Coarse, dry skin, anaemia, yellow discolouration of
- hypercarotenaemia (in hypothyroidism)
- Areas of vitiligo (seen in association with autoimmune disorders such as Grave’s disease)
- Fine tremor – place sheet of paper on outstretched hands
Pulse
- Rate, rhythm
- Tachycardia or atrial fibrillation in hyperthyroidism
- Bradycardia in hypothyroidism
Blood pressure:
Pemberton’s sign:
- Lift both arms as high as possible.
Patients with large retrosternal goitres develop signs of congestion (plethora) & cyanosis on raising their arms above their heads, leading to suffusion of face, giddiness or syncope.
Eyes:
- Loss/thinning of hair on outer 1/3 of eyebrows (hypothyroidism)
- Periorbital oedema (hypothyroidism)
- Test visual acuity & visual fields.
- Anaemia
- Eye movements – ophthalmoplegia, diplopia
- Exopthalmos – whiteness of sclera visible below the iris
- Lid retraction – sclera visible above the iris
- Proptosis – eye protrusion beyond level of supraorbtial ridge
- Chemosis – conjunctival oedema
- Lid lag
THYROID EXAMINATION PROPER:
- INSPECTION:
- Examine front of neck – goitre, symmetry, skin changes, scar
- Ask patient to open his mouth & stick his tongue out at far as possible. If the lump moves on protrusion, it is likely to be a thyroglossal cyst.
- (Ask patient to swallow – thyroid & thyroglossal cyst will rise during swallowing)
2. PALPATION:
Best performed from behind
- Ask patient to take a sip of water, hold it in his mouth & swallow when asked. Feel the thyroid gland rise.
- Consider the size, symmetry, consistency, tenderness & mobility.
- Try to work out whether the thyroid is diffusely enlarged or nodular.
- Palpate the cervical lymph nodes – may be involved in thyroid cancer.
3. PERCUSSION:
- Over the sternum, from notch downwards. A change in resonant to dull indicates a possible retrosternal goitre.
4. AUSCULTATION:
- Listen for bruits over each lobe
Upper/lower limbs
- Proximal myopathy
- Reflexes (slow, relaxing - hypothyroid)
Tibia
- Pretibial myxoedema
- Consider the main differential diagnosis of a thyroid goitre:
_ Simple goitre (iodine deficiency)
_ Thyroid adenoma (follicular commonest)
_ Multinodular goitre
_ Thyroid carcinoma (papillary > follicular > anaplastic > medullary)
_ Thyroiditis (Hashimotos, De-Quervains)
_ Graves disease
The most informative diagnostic test if asked, is TSH level – don’t say ‘thyroid function tests’
Investigate with ultrasound and fine needle aspirate, or core biopsy.
Consider the differential diagnosis of neck lump and additional steps to conduct in the examination:
_ Lymphadenopathy – remember the jugulodigastric node which is the sentinel node for many head and neck carcinomas, so LOOK IN THE MOUTH – you would look silly to miss out on an obvious tongue tumour!
_ Branchial cyst – anterior to upper 1/3 sternocleidomastoid
_ Thyroglossal cyst – cyst in the embryological passage of thyroid from posterior tongue. Moves up on protrusion of tongue
_ Cystic hygroma – cystic degeneration of lymphatics commonly found in babies
_ Submandibular gland – arises from under the posterior mandible. The commonest cause of unilateral enlargement is stone in duct, so MUST palpate with gloved finger, under tongue, where duct opens onto the floor of the mouth, and bimanual palpation can be conducted, including potentially palpating the calculus. Other causes include neoplasia both benign and malignant.
_ Parotid gland – overlies the angle of the jaw. Stensons duct opens opposite to the upper 2nd molar teeth, and should be inspected and palpated intra-orally.
Common causes of enlargement include: sjogrens, sarcoidosis, mumps, duct calculi. Neoplasia is commonest – benign pleomorphic adenoma being commonest, followed by Warthins tumour, commonly affecting the older patient. Cystic adenoid carcinoma is commonest malignant neoplasm. You must assess the facial nerve which passes through the gland – expecting a lower motor neurone lesion – although recognise that individual nerves can be affected preserving others (temporal, zygomatic, buccal, mandibular, cervical).
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