Brain abscess Histology and Explanation

Abscess is an exudative purulent localized inflammation. In the white matter, a recent abscess consisting in pus : neutrophils (normal or in lisis), fibrin, necrotic debris, germs. Vessels present congestion and important perivascular edema. (Hematoxylin-eosine, ob. x4)

This is a cerebral abscess. There is a liquefactive center with yellow pus surrounded by a thin wall. Abscesses usually result from hematogenous spread of bacterial infection, but may also occur from direct penetrating trauma or extension from adjacent infection in sinuses

This trichrome stain demonstrates the light blue connective tissue in the wall of an organizing cerebral abscess. Normal brain is at the right and the center of the abscess at the left