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Monday, February 7, 2011

Mostly Asked Pathology Multiple choice questions (MCQs)

Answers are given at the end of this post

Patients with hashimoto thyroiditis are at increase risk for developing

A)Papillary thyroid carcinoma

B)Follicular thyroid carcinoma

C)B cell non Hodgkin lymphoma

D)Hodgkin lymphoma

E)Medullary carcinoma



All lesions of thyroid can b diagnosed on fine needle cyto except

A)Papillary thyroid carcinoma

B)Follicular thyroid carcinoma

C)Medullary carcinoma

D)Anaplastic carcinoma

E)Hodgkin lymphoma



Difference between follicular ca and follicular adenoma can be

A)Capsular vascular invasion

B)Metastasis

C)Calcification foci

D)RAS mutation

E)Central fibrosis



Low TSH, high T3 and T4 is possible in all except

A)Endemic goiter

B)glaucomatous throiditis

C)Subacute lymphocytic thyroiditis

D)hashimoto thyroiditis

E)Graves’s disease



All can b seen in diabetic nephropathy except

A)Hyaline arteriolosclerosis

B)Nodular glomerulosclerosis

C)Diffuse mesengial sclerosis

D)granulomatous pyelonephritis

E)necrotizing papillitis


ACTH levels are elevated and cannot be suppressed by low dose of dexamethasone but respond with higher dose of dexamethasone in case of

A)Ectopic ACTH

B)Adrenal tumor

C)Pituitary located tumor

D)Paraneoplastic syndrome

E)None of these


Patient with intractable peptic ulcers can be suspected for

A)adrenal tumor

B)tumor of islets of langerhens

C)MEN 2A

D)MEN 2B

E)Pituitary tumor

medullary carcinoma of thyroid initially manifest with

A)hypocalcemia

B)hypercalcemia

C)vomiting

D)Diarrhea

E)Hyperthyroidism

Antibodies central for graves disease is

A)TSI

B)TGI

C)TBIT

D)TSHR

E)LATS

Benign localized hyperplasia of melanocytes and common in infancy and childhood is

A)Vitligo

B)Frenkles

C)Lentigo

D)Melanocytic nevus

E)melasma

Verruca valgaris is caused by which virus

A)EBV

B)HPV

C)Smallpox

D)Chickenpox

E)Rubeolla



One of the following is not bullous or blistering disease of skin

A)pemphigus

B)bullous pemphigous

C)dermatitis herpetiformis

D)porphyria

E)discoid lupus erthematosis


Premalignant condition of skin is

A)actinic keratosis

B)dysplastic nevi

C)seborrheic keratosis

D)acanthosis nagricans

E)keratocanthoma


Molluscum contagiosum

A)EBV

B)HPV

C)Pox virus

D)Chickenpox

E)Rubeolla

Basal cell ca of eyelid

A)2nd most common Ca of eyelid

B)Predilection for lower eyelid

C)Predilection for upper eyelid

D)None of these

E)Both a and b



Necrotic dead piece of bone is

A)involvecrum

B)sequestrum

C)woven bone

D)lamellar bone

E)cancellous bone



Unmeneralised bone is called

A)osteoid

B)involvecrum

C)woven bone

D)lamellar bone

E)cancellous bone


Primary osteogenic tumor is

A)osteoblastoma

B)chondroblastoma

C)Ewing tumor

D)giant cell tumor

E)multiple myeloma



Achodrogenesis type II defect in

A)Collagen type 1

B)Collagen type 2

C)Collagen type 3

D)Collagen type 4

E)Collagen type 5

All seen in juvenile rheumatoid arthritis except

A)RA factor present

B)Begins before 16 year

C)Oligoarthritis is common

D)Large joints are affected

E)Rheumatoid nodules absent



All factors of these stimulate osteoblast except

A)Endothelial factor

B)IGF

C)TGF

D)PDGF

E)IL


Primary small bone cell tumor

A)osteoblastoma

B)chondroblastoma

C)Ewing tumor

D)giant cell tumor

E)multiple myeloma


Patient with acute pain in foot , that aggravated with alcohol intake relieved for many years without medicines it can be

A)osteogenic imperfecta

B)reactive arthritis

C)supparative arthritis

D)acute gout

E)synovial cyst


Reinke’ crystalloids characteristic present in

A)leydig cell tumor

B)sertoli cell tumor

C)gonadoblastoma

D)testicular lymphoma

E)seminoma


ITGCN not seen in

A)Seminoma

B)Spermatocytic seminoma

C)Embryonal carcinoma

D)Yolk sac tumor

E)Choriocarcinoma


Which one can be stated as extra embryonal germ cell carcinoma

A)Seminoma

B)Spermatocytic seminoma

C)Embryonal carcinoma

D)Yolk sac tumor

E)Teratoma



27. In urinary bladder carcinoma, invasion of muscularis propria shows grade

A)T1

B)T2

C)T3

D)T4

E)T5


In bowen and bowenoid diseases difference is that bowenoid is

A)Not invasive

B)Invasive

C)Occurs in older persons

D)Solitary lesion

E)Non pigmented


Regarding gullian barre syndrome

A)5 cases per 1 lace in usa

B)Descending paralysis

C)Polyrediculoneuropathy

D)Causative agent polio virus

E)Deep tendon reflex exaggerated



30. In renal failure GFR reduces to

A)50%

B)20-50%

C)20-25%

D)10%

E)5%



31.False regarding Duchene disease

A)less severe than Becker disease

B)most common

C)x linked

D)dystrophin is affected

E)all these are true



32.Regarding nerve regeneration

A)the proximal segment of degenerated axons sprouts and elongate

B)the distal segment of degenerated axons sprouts and elongate

C)grow 1 cm per day

D)regenerating clusters are not formed

E)muscle reinnervation is not associated



33. It is not a reaction of muscle to nerve injury

A)Segmental necrosis

B)Vacoulisation

C)Regeneration

D)Hypertrophy

E)Dystrophy



34.Analgesic nephropathy complicated to

A)renal failure

B)malignancy

C)papillary necrosis

D)chronic tubulointerstial

E)none of these



35.Correct about ARPKD

A)kidney is small

B)is present in adults

C)also called medullary sponge kidney

D)dilated channels are right angle to cortical surface

E)kidneys are irregular in appearance


36. Kidney secretes all except

A)Renin

B)Insulin

C)Erythopoitein

D)a & c



37.In anti GBM antibody induced nephritis, the deposits are

A)Linear

B)Granular

C)Lumpy

D)Spiked

E)Subepithelial


38. Complication of renal cystic dysplasia

A)Chronic renal failure

B)Uteropelvic obstruction

C)Ureteral agenesis

D)Ureteral stenosis

E)Liver cystic disease



39.In focal segmental G. sclerosis deposits contain

A)Igm and c3

B)Iga and c3

C)Only Iga

D)Iga Igg and c3

E)Igm iga and c3


40.A aptient with hematuria , flank pain , fever , dysuria, if infection is suspected then diagnosis confirmed by

A)urine DR

B)pus casts

C)quantitive urine culture

D)ultrasound

E)none of these



41.Patient history of bladder cancer , his occupation would be worker at

A)plastic factory

B)rubber factory

C)dye factory

D)coal mine worker

E)arsenic industry


42.Amyloid deposits in kidney is stained with

A)Masson trichrome

B)Congo red

C)Methylene blue

D)H & E Stain

E)Persian blue



43.Causative agent for staghorn calculi in kidney is

A)proteus

B)e coli

C)streptococcus

D)uric acid

E)cysteine



44.Regarding malignant nephrosclerosis

A)hyaline arteriolosclerosis occur

B)gross kidney leathery appearance

C)cortical shrinking and scarring

D)all of the above

E)hyperplasic retinopathy



45.All are important in etiology of membranous GN except

A)atopy

B)malignancies

C)drugs

D)infections

E)SLE

46.IgA nephropathy mostly presents as

A)ARF

B)Necrotising pappilitis

C)Recurrent haematuria

D)Acute nephrotic syndrome

E)Nephritic syndrome

47.Dilation of renal pelvis and calyces associated with progressive atrophy of the kidney due to obstruction to outflow of urine is

A)hydrnephrosis

B)necrotizing papplitis

C)papillary necrosis

D)pyelonephritis

E)pyonephrosis


48.The main cause of renal dysfunction in multiple myeloma is

A)hypercalcemia

B)urinary tract obstruction

C)hyperurecemia

D)bence jones protein

E)pyelonephritis



49.In acute nephritic syndrome the cardinal symptom is

A)proteinuria

B)generalised edema

C)severe HTN

D)lipidemia

E)gross haemtuia



50. Renal cell carcinoma most commonly metastasize to

A)Lungs

B)Lymph nodes

C)Adrenals

D)Bones

E)liver

ANSWERS:

1-C)

2-B)

3-A)

4-A)

5-D)

6-C)

7-B)

8-D)

9-D)

10-C)

11-B)

12-E)

13-A)

14-C)

15-B)

16-B)

17-A)

18-A)

19-B)

20-A)

21-A)

22-C)

23-D)

24-A)

25-B)















26-D)

27-B)

28-A)

29-C)

30-C)

31-A)

32-A)

33-E)

34-B)

35-D)

36-B)

37-A)

38-A)

39-A)

40-C)

41-B)

42-B)

43-A)

44-E)

45-A)

46-E)

47-A)

48-D)

49-E)

50-A)

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